|
Maximum Likelihood Method on The Construction of
5 s& ~2 D3 V+ D' T4 ~" G0 bPhylogenetic Tree for Identification the Spreading of " @# z' W- E! E* H
SARS Epidemic " Y9 M: f7 q# B4 V5 ~6 c' Z5 r
; Q9 U' k6 o# }, M$ W2 u3 U
( Y* V2 _7 ^4 B4 e# \0 ?There are several phylogenetic tree construction
1 G1 I5 l* g( }$ Z2 o6 }" imethods that can be used to illustrate the spread of disease . G7 u+ G" v1 c
epidemics. One of the methods used is probability-based " u. O- L2 E' w
maximum likelihood. This paper explains how to identify the ' H D* ~! D" C
spread of the SARS epidemic in the world using the formation of
+ @8 x9 X. ^6 j# q: Y) m/ rphylogenetic trees using the maximum likelihood method. The ) `( o8 X( _- Y8 u' o
output obtained was a description of the spread of SARS virus 4 G9 I! ]! C, C# Q, j/ v' a( E
with the selection of tree candidates after performing a heuristic ( C# Q m' R* q4 n' \
search of the Stepwise Addition method. The result of the research
- W5 ^( y6 k% P: R/ t* ^+ D! V) ~showed that the closest distance to the palm civet is GZ 02/18/03
+ O- O" J# x8 O, i# |indicating that the initial spread of the SARS epidemic started
0 V/ u9 Z8 _0 a- Gfrom Guangzhou.
" T7 q- t8 H# g9 X. h/ u
- a2 _+ A6 j4 c8 f: P$ H: a6 L4 G: l! g t' Z/ n/ x
$ F: x! V+ b7 ?
|