|
Maximum Likelihood Method on The Construction of ' D# J4 k; Q% o7 F4 l
Phylogenetic Tree for Identification the Spreading of
5 [4 ]! s& O% {SARS Epidemic
?* |& ? j5 Q. n" T/ A
" r5 v, I0 ^; z0 s. O! z0 }8 @0 ?. V1 d8 S
There are several phylogenetic tree construction
) H0 K4 C; H9 ]. B6 Tmethods that can be used to illustrate the spread of disease
7 D7 Y( d$ _/ ~. }3 @epidemics. One of the methods used is probability-based
9 k, F, l0 h$ T# G1 |maximum likelihood. This paper explains how to identify the 9 c& N, N7 F1 [ X3 Y
spread of the SARS epidemic in the world using the formation of
8 V+ d' s2 I/ N- k3 k! _phylogenetic trees using the maximum likelihood method. The ! G: y- Z" @ g/ @
output obtained was a description of the spread of SARS virus 7 A& f, b& G, _6 b
with the selection of tree candidates after performing a heuristic 2 a. A3 P1 B t+ C. T
search of the Stepwise Addition method. The result of the research 3 W$ \9 S3 h6 t3 Y# z6 Y7 t
showed that the closest distance to the palm civet is GZ 02/18/03
7 m$ V' |* z3 m1 c, Nindicating that the initial spread of the SARS epidemic started
4 l, a* v1 t. v) [; H b; lfrom Guangzhou.
* X- X: ?- e4 J
9 l' X6 X8 G |
( B" p. @, ]; N6 S: v6 W
& ^" F' y `, {0 U, _! M1 [ |