Maximum Likelihood Method on The Construction of Phylogenetic Tree for Ident...

杨利霞

Maximum Likelihood Method on The Construction of

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Phylogenetic Tree for Identification the Spreading of

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SARS Epidemic

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; g2 U. I- q* P3 L* x& VThere are several phylogenetic tree construction
' u% _& C  Q' m. Jmethods that can be used to illustrate the spread of disease
epidemics. One of the methods used is probability-based
% n+ o: I( v) umaximum likelihood. This paper explains how to identify the
: Q/ f* u+ q* ~  s) Nspread of the SARS epidemic in the world using the formation of
! g; q! \( H4 F/ i% t7 E8 m3 Hphylogenetic trees using the maximum likelihood method. The
output obtained was a description of the spread of SARS virus
with the selection of tree candidates after performing a heuristic
; l8 H& L+ [" o* Q$ m4 q, ssearch of the Stepwise Addition method. The result of the research
showed that the closest distance to the palm civet is GZ 02/18/03
indicating that the initial spread of the SARS epidemic started
from Guangzhou.


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