一个美国教授写的B题第二问答案(求助,用SAS做的,我看不懂!) 我贴在我的博客里了 http://blog.sina.com.cn/u/1244765643 是从一个美国网站上找到的,真的看不懂,因为不会用SAS 另外,请看懂的或者看明白了的同仁能慷慨一下 与我联系联系 教教我 真的很急!!! 在这里先谢了!! PS:本来前天就搜到了的 但是老师不让外传 但现在实在来不及了 我们明天8点交卷 我现在在武汉 就算不行也希望和大家交个朋友 下面是一些片段 Repeated CD4 counts data from AIDS clinical trial.
Source: AIDS Clinical Trial Group 193A Study. Data courtesy of Dr. Keith Henry. Reference: Henry, K., Erice, A., Tierney, C., Balfour, H.H. Jr, Fischl, M.A., Kmack, A., Liou, S.H., Kenton, A., Hirsch, M.S., Phair, J., Martinez, A. and Kahn J.O. for the AIDS Clinical Trial Group 193A Study Team (1998). A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 19, 339-349. Description:
The data are from a randomized, double-blind, study of AIDS patients with advanced immune suppression (CD4 counts of less than or equal to 50 cells/mm^3). Patients in AIDS Clinical Trial Group (ACTG) Study 193A were randomized to dual or triple combinations of HIV-1 reverse transcriptase inhibitors. Specifically, patients were randomized to one of four daily regimens containing 600mg of zidovudine: zidovudine alternating monthly with 400mg didanosine; zidovudine plus 2.25mg of zalcitabine; zidovudine plus 400mg of didanosine; or zidovudine plus 400mg of didanosine plus 400mg of nevirapine (triple therapy). Measurements of CD4 counts were scheduled to be collected at baseline and at 8-week intervals during follow-up. However, the CD4 count data are unbalanced due to mistimed measurements and missing data that resulted from skipped visits and dropout. The number of measurements of CD4 counts during the first 40 weeks of follow-up varied from 1 to 9, with a median of 4. The response variable is the log transformed CD4 counts, log(CD4 counts + 1), available on 1309 patients. The categorical variable Treatment is coded 1 = zidovudine alternating monthly with 400mg didanosine, 2 = zidovudine plus 2.25mg of zalcitabine, 3 = zidovudine plus 400mg of didanosine, and 4 = zidovudine plus 400mg of didanosine plus 400mg of nevirapine. The variable Week represents time since baseline (in weeks). Variable List: Subject ID, Treatment, Age (years), Gender (1=M, 0=F), Week, log(CD4 count + 1).
1 2 36.4271 1 0.0000 3.13549421590 1 2 36.4271 1 7.5714 3.04452243770 1 2 36.4271 1 15.5714 2.77258872220 1 2 36.4271 1 23.5714 2.83321334410 1 2 36.4271 1 32.5714 3.21887582490 1 2 36.4271 1 40.0000 3.04452243770 2 4 47.8467 1 0.0000 3.06805293510 2 4 47.8467 1 8.0000 3.89182029810 ......
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