|
Maximum Likelihood Method on The Construction of # `1 [: n) r5 Q- q/ r& E/ C! j4 X
Phylogenetic Tree for Identification the Spreading of ( y2 ` d+ {% |0 ` d, n3 s
SARS Epidemic 2 D4 D# @6 U8 T' e9 @1 I0 D
/ F+ Z* ~' i2 D' a, H
8 g$ G7 m4 b+ P! Y
There are several phylogenetic tree construction 6 G/ z5 a4 q2 F Z2 K5 S! o6 }
methods that can be used to illustrate the spread of disease
4 X& L/ |; f4 @- A8 j" s' ]epidemics. One of the methods used is probability-based
: F" k- S0 U' V0 u+ ^; V& Nmaximum likelihood. This paper explains how to identify the ( |5 l6 m7 f o! U) d) i. z: Q9 G
spread of the SARS epidemic in the world using the formation of 6 E3 _5 Y& D5 X, ~9 `8 j1 I
phylogenetic trees using the maximum likelihood method. The
# }" m( h. H! g( d0 u8 g5 Q! g$ Poutput obtained was a description of the spread of SARS virus # v2 ^5 y" E3 K x3 O/ U
with the selection of tree candidates after performing a heuristic
9 X. k$ M7 s0 n) lsearch of the Stepwise Addition method. The result of the research $ f9 p/ F: z6 A J' e
showed that the closest distance to the palm civet is GZ 02/18/03 , `5 @3 Y4 B9 G: K. B
indicating that the initial spread of the SARS epidemic started 3 S' B" T) ?% v* J( i# d
from Guangzhou.
. P$ B7 C) z4 x6 \0 d( H
1 \. q; k8 @3 S4 l2 k: T( ]3 A2 F/ ?" R) z. G. P, H: x
|