|
Maximum Likelihood Method on The Construction of % m( z) r( q0 f$ M
Phylogenetic Tree for Identification the Spreading of 4 k. h+ v8 @; H$ R/ f3 Q; J; t/ B
SARS Epidemic ! h" h6 m. T/ R8 u
W& W) i: |- T- j2 Y$ p( ~7 W6 ^
% m. F9 P' t: W; T# XThere are several phylogenetic tree construction 7 J, V+ G% e1 _. X2 g: R! i
methods that can be used to illustrate the spread of disease
* ^! v$ \/ o( J! D) k$ ~epidemics. One of the methods used is probability-based & A: d+ Y, ?8 x
maximum likelihood. This paper explains how to identify the
3 ` `4 f" I& v: vspread of the SARS epidemic in the world using the formation of / q4 M* m6 `1 e k
phylogenetic trees using the maximum likelihood method. The : Q6 T0 E: p0 [
output obtained was a description of the spread of SARS virus ) n8 W, l& a s# M. m5 ?
with the selection of tree candidates after performing a heuristic
& q. l0 E) C$ p9 osearch of the Stepwise Addition method. The result of the research 8 V+ y4 T! j; L4 P5 M8 K. X
showed that the closest distance to the palm civet is GZ 02/18/03
9 J" C/ C& Y. t2 W: `3 Rindicating that the initial spread of the SARS epidemic started
- Y# {/ f# a4 ? q$ `from Guangzhou.
; B* o7 I$ H# P. ]; P) k' w# ^6 n5 D# ]
" {- \7 ?1 f7 ?4 S0 S) Y! Q
|