|
Maximum Likelihood Method on The Construction of
* |( K3 f. L1 R2 ^Phylogenetic Tree for Identification the Spreading of , W7 x( r+ Y1 d4 c, }" R# i
SARS Epidemic ! A: Z- Y. N/ S% n6 h4 M1 ]8 k
; W( U( L- q+ c: e, y/ t! p5 R- J8 c5 r! Q5 ~
There are several phylogenetic tree construction % v9 D' F: `+ v- G
methods that can be used to illustrate the spread of disease $ a& y1 u5 w Q+ i4 j/ Q, o# d9 B
epidemics. One of the methods used is probability-based " Q2 @. @9 t+ `) a; s9 K9 J, P
maximum likelihood. This paper explains how to identify the + c1 \) g& Y* K$ P, l% P" J- N7 Z
spread of the SARS epidemic in the world using the formation of * ?9 s7 k4 N: ^, N
phylogenetic trees using the maximum likelihood method. The
( V7 h F# h/ z, @1 M- ~output obtained was a description of the spread of SARS virus
3 b, s9 M7 B- O# F5 t% I' vwith the selection of tree candidates after performing a heuristic 6 H+ w6 Z: s q! }# \0 b
search of the Stepwise Addition method. The result of the research ) [' @( w# {$ |- s5 q" K9 w7 g1 M
showed that the closest distance to the palm civet is GZ 02/18/03 [5 J; P& I# X% x# P7 [! m
indicating that the initial spread of the SARS epidemic started
( _, H0 h( J ]- Q* z Ifrom Guangzhou.
- s" N4 s# E. h" X( ^3 T. `
2 J* t) L3 L$ T: g, W
" \! [, ]7 B8 f+ t1 J. f |