|
Maximum Likelihood Method on The Construction of " K* C0 v( c1 V0 X
Phylogenetic Tree for Identification the Spreading of 8 _3 U- q# J% n- Z' M
SARS Epidemic , l7 Y4 n9 w6 U6 }1 _+ h
5 t. b; g# I# d" K8 `3 T' {( B# E" J" s) k! ?
There are several phylogenetic tree construction
. N/ V* T' z+ z5 `methods that can be used to illustrate the spread of disease $ \+ r8 A" } L4 L$ z. I
epidemics. One of the methods used is probability-based
. n+ C5 M2 L9 W( q0 C( ~3 vmaximum likelihood. This paper explains how to identify the
- T1 S% U. h& a! H) y) I3 X: vspread of the SARS epidemic in the world using the formation of " g# t0 ]: y; r/ m+ f/ M3 W
phylogenetic trees using the maximum likelihood method. The
! `5 ^" i/ S2 Q3 k* \4 i: poutput obtained was a description of the spread of SARS virus
6 P( s; i+ h# Vwith the selection of tree candidates after performing a heuristic / q. ]* L! Y8 T) [* T
search of the Stepwise Addition method. The result of the research : I; K4 ^- R5 ]! U: p: X l0 f
showed that the closest distance to the palm civet is GZ 02/18/03
N. ?& g& H7 x2 h1 Sindicating that the initial spread of the SARS epidemic started 2 V" s3 f8 T! M8 S2 j
from Guangzhou. 7 \" }8 f" ?& O
" a5 l* d* H n6 l# w
8 {7 _, D7 r8 ?$ m1 x$ A |