|
Maximum Likelihood Method on The Construction of 4 S5 |. I" T% g S, A) m
Phylogenetic Tree for Identification the Spreading of - o) w. q, J8 x# E
SARS Epidemic
! A s! X9 L2 Z0 [6 R6 c) k! j
6 G1 }: N/ k. X; G- M
9 y. a! C7 B/ t$ {5 k: rThere are several phylogenetic tree construction 1 g' C- ~ w7 K& x4 ~9 `3 `
methods that can be used to illustrate the spread of disease
( E j4 ]. J% x3 T$ i8 depidemics. One of the methods used is probability-based 7 T5 h; K5 @4 N3 x
maximum likelihood. This paper explains how to identify the + s4 J7 g! W5 I& m
spread of the SARS epidemic in the world using the formation of + ?! A/ W8 n. F" I- y9 @
phylogenetic trees using the maximum likelihood method. The f( b' ~/ u' m
output obtained was a description of the spread of SARS virus
' ]* @6 C' u" D1 Q- U- Z( C( Rwith the selection of tree candidates after performing a heuristic
% H" y" A; Q( Csearch of the Stepwise Addition method. The result of the research
0 t+ K+ k( D3 P0 x; a: p9 Oshowed that the closest distance to the palm civet is GZ 02/18/03
& y/ i }+ w) [5 _5 iindicating that the initial spread of the SARS epidemic started
4 ~$ c: _* \$ s, E* M% tfrom Guangzhou. $ @% @/ O! {0 r( }
1 N8 Z5 B8 ^& M
/ B7 \7 k$ m0 ~9 [+ m! } |