Maximum Likelihood Method on The Construction of Phylogenetic Tree for Ident...

杨利霞

Maximum Likelihood Method on The Construction of

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Phylogenetic Tree for Identification the Spreading of

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SARS Epidemic

+ M" ]- U. \$ u& U  I3 ?There are several phylogenetic tree construction
1 U+ n0 ?% s) `2 F' Pmethods that can be used to illustrate the spread of disease
epidemics. One of the methods used is probability-based
' F' O' h5 P" n$ Vmaximum likelihood. This paper explains how to identify the
  i( u2 v- c2 J( s$ M# ispread of the SARS epidemic in the world using the formation of
5 Z3 m2 S2 f" ^0 Cphylogenetic trees using the maximum likelihood method. The
" o% ^; k* l7 houtput obtained was a description of the spread of SARS virus
& ]. J" ]( V9 d: K6 a. L4 j" Mwith the selection of tree candidates after performing a heuristic
( c* G+ I" K* i6 ~! J- ssearch of the Stepwise Addition method. The result of the research
showed that the closest distance to the palm civet is GZ 02/18/03
. \1 r4 r. e. v. B/ u5 r  Dindicating that the initial spread of the SARS epidemic started
1 X! u# F% q& O( m$ X! L, dfrom Guangzhou.
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