|
Maximum Likelihood Method on The Construction of
+ h5 f2 o2 \& pPhylogenetic Tree for Identification the Spreading of 4 T% I1 I8 D2 Z0 {" w0 g) x
SARS Epidemic * R8 R- J: ~ y# n; q
0 R% q' o6 k! b$ Z+ Q# {
8 f. w. t& o+ s4 Y, N5 G" OThere are several phylogenetic tree construction ) ^# _8 G- M( i t1 u
methods that can be used to illustrate the spread of disease 0 H: }3 i6 _$ Q$ h) E
epidemics. One of the methods used is probability-based , Y1 r6 Z+ Y. h2 @0 f
maximum likelihood. This paper explains how to identify the
1 P8 [" |7 W$ E1 c9 ospread of the SARS epidemic in the world using the formation of
% j/ T! B, `! `$ F. ]1 @9 Pphylogenetic trees using the maximum likelihood method. The
0 g: L6 |$ }7 v8 Zoutput obtained was a description of the spread of SARS virus
: g4 G( V- H6 p/ awith the selection of tree candidates after performing a heuristic
' J s! F6 M; N7 f2 d! W. s. P; Zsearch of the Stepwise Addition method. The result of the research
) s" y* u- g5 {4 E# lshowed that the closest distance to the palm civet is GZ 02/18/03 $ V- w6 D2 \) h1 L
indicating that the initial spread of the SARS epidemic started / c# A$ w! i0 t! B
from Guangzhou. 4 ]8 D0 {) [: `8 Z9 B5 F3 a# N- v
' Y! \5 o5 m; ^5 a
2 O+ d! }0 X0 H+ j. D |