|
Maximum Likelihood Method on The Construction of : l+ X- K. w. }7 b0 f0 I
Phylogenetic Tree for Identification the Spreading of
0 b: E# C1 ]: |/ v/ D# a1 \8 V5 j$ j! M/ FSARS Epidemic $ ~$ C3 o9 e1 P
$ M. ?+ ~) d. M8 ]# Y9 ]9 X6 A9 }& Z7 i% m3 V- _
There are several phylogenetic tree construction
! q% [& N- H4 o6 O, N; wmethods that can be used to illustrate the spread of disease
# L5 j0 R9 a% ~" tepidemics. One of the methods used is probability-based ( \5 z* T0 _9 T# S
maximum likelihood. This paper explains how to identify the
! n" E7 q* u- }spread of the SARS epidemic in the world using the formation of 3 O+ f# v- Q, o6 c/ H) ]7 g
phylogenetic trees using the maximum likelihood method. The
r4 w3 ]% S! `output obtained was a description of the spread of SARS virus
5 e7 G0 K* {0 A3 q9 g8 _with the selection of tree candidates after performing a heuristic
# ^. k2 |# X E' ^: jsearch of the Stepwise Addition method. The result of the research
y. i: L) J! [showed that the closest distance to the palm civet is GZ 02/18/03 * w% o! C2 f9 C g& |: T- r5 j2 b% z
indicating that the initial spread of the SARS epidemic started
" k) b) j6 X; Y6 B) Ufrom Guangzhou. ( w X. [+ {7 T; m
. [ T7 X. [0 O4 u- Y, z' o
9 P+ m+ S8 C, F+ v
|