|
Maximum Likelihood Method on The Construction of
. y- t% R1 Q$ t1 fPhylogenetic Tree for Identification the Spreading of
7 Q2 U' N7 W2 u y/ j* sSARS Epidemic ! {* L/ f7 e9 o" l, j
0 R) F+ q4 k8 _& p2 k S* M
`6 O. C- R$ e4 [There are several phylogenetic tree construction * s* }, V7 e, {8 e
methods that can be used to illustrate the spread of disease
8 T% F/ r) S. T. A I3 v# _epidemics. One of the methods used is probability-based ' y5 U/ e( t8 h# b+ l" b$ R
maximum likelihood. This paper explains how to identify the 7 ~4 A/ V, e2 b& J H: O
spread of the SARS epidemic in the world using the formation of ) O. r* A: z- d3 W9 R$ V0 a6 l) S
phylogenetic trees using the maximum likelihood method. The ?# `5 M/ M9 W
output obtained was a description of the spread of SARS virus
: e' c% m+ _5 D; qwith the selection of tree candidates after performing a heuristic
( q$ [2 m* s$ }9 f4 M& wsearch of the Stepwise Addition method. The result of the research
8 z* B$ R/ D6 cshowed that the closest distance to the palm civet is GZ 02/18/03
7 J# n5 z1 U! s$ [indicating that the initial spread of the SARS epidemic started
6 |6 }- O8 m* _' j! o- z2 [4 efrom Guangzhou.
. @ C2 Y$ [0 V' U
1 M4 \8 n7 I4 W. {
; ~# G S" n( d0 ~5 w |