Maximum Likelihood Method on The Construction of Phylogenetic Tree for Ident...

杨利霞

Maximum Likelihood Method on The Construction of

Phylogenetic Tree for Identification the Spreading of

! o  u) t# W3 }. K4 s$ A& q( c. ]

SARS Epidemic

  X; t, \$ K  w% z. G
$ Y, M0 U9 }9 ?$ v. ?( q  \6 A
) K/ N/ f+ f# b. WThere are several phylogenetic tree construction
methods that can be used to illustrate the spread of disease
( ^, e( X2 q7 x" mepidemics. One of the methods used is probability-based
4 \  d; W; q6 e. ]2 `7 _: p9 rmaximum likelihood. This paper explains how to identify the
( O$ S/ d& u, d6 Wspread of the SARS epidemic in the world using the formation of
phylogenetic trees using the maximum likelihood method. The
output obtained was a description of the spread of SARS virus
with the selection of tree candidates after performing a heuristic
search of the Stepwise Addition method. The result of the research
showed that the closest distance to the palm civet is GZ 02/18/03
indicating that the initial spread of the SARS epidemic started
% k6 O2 r! h: q5 v# C# sfrom Guangzhou.
& \2 b% t2 B7 y) W- [- v7 l" G2 M
6 |3 }7 s) g* G+ S+ p* ^
8 }3 d3 C% E. Z3 @